博士/讲师

邮箱：rupengbu@163.com

● 2022.08 - 至今，生物制药研究院，讲师

● 2018.09 - 2022.06, 中国工程物理研究院化工材料研究所, 材料科学与工程, 博士

● 2017.07 - 2018.01，山东一诺威聚氨酯股份有限公司

● 2015.08 - 2017.06, 中国工程物理研究院化工材料研究所，安全工程，硕士 

● 2014.09 - 2017.06, 中北大学, 安全工程, 硕士

● 2010.09 - 2014.06, 聊城大学, 安全工程, 学士

● 计算含能材料学

● 药物/含能材料晶体工程

● 药物/含能材料共晶制备

● 药物/含能材料多晶型筛选

● 药物/含能材料晶体形貌控制

1.国家自然科学基金委员会, 青年基金，2250100，平面层状含能晶体中分子间相互作用的拓扑机制与理性设计研究，2026-01-01至2028-12-31，30万，在研，主持

2.聊城大学博士及高层次人才科研启动基金，2023.12 - 2025.12，16万，主持

3. 国家自然科学基金委员会, 面上项目, 22175158, LLM-105晶体的微纳多级结构构筑及其形成机制研究, 2022-01-01 至 2025-12-31, 60万元, 在研, 参与

4. 国家自然科学基金委员会, 面上项目, 22173086, 含能化合物本征热稳定性的预测方法与应用研究, 2022-01-01 至 2025-12-31, 61万元, 在研, 参与

5. 国家自然科学基金委员会, 面上项目, 21975236, 缺陷微结构对CL-20热致相变影响的机理研究, 2020-01-01 至 2023-12-31, 66万元, 在研, 参与

6.达格列净口服片剂开发及质量控制关键技术研究——达格列净口服片剂药品上市注册现场考核技术支持，2024-12-16-2026-12-16，10万，横向课题，在研，主持

(1) Bu, R. P. Rational design of planar lamellar energetic crystals via intermolecular interaction engineering: Synergistic mechanisms for balancing energy and safety. Defence Technology 2026, 57, 280–299. 

(2) Bu, R. P.; Xiong, Y.; Zhang, C. Y. π-π Stacking Contributing to the Low or Reduced Impact Sensitivity of Energetic Materials. Cryst. Growth Des. 2020, 20(5), 2824–2841.

(3) Bu, R. P.; Xiong, Y.; Zhang, C. Y. Hydrogen Bonding in CHON-Containing Energetic Crystals: A Review. Cryst. Growth Des. 2019, 19(10), 5981–5997.

(4) Wang, T. Y.; Bu, R. P.*; Wang, Z. P*. Molecular insights into solubility and crystallization of d-ribose in alcohols: combined experimental and electrostatic potential analysis. Chem. Eng. Commun. 2026, Early Access.

(5) Bu, R. P.; Li, H. Z.; Zhang, C. Y. Polymorphic Transition in Traditional Energetic Materials: Influencing Factors and Effects on Structure, Property, and Performance. Cryst. Growth Des. 2020, 20(5), 3561–3576.

(6) Liu, G. R.; Bu, R. P.; Zhang, C. Y. Energetic Cocrystallization as the Most Significant Crystal Engineering Way to Create New Energetic Materials. Cryst. Growth Des. 2022, Early Access.

(7) Bu, R. P.; Jiao, F. B.; Zhang, C. Y. Categorizing and Understanding Energetic Crystals. Cryst. Growth Des. 2021, 21(1), 3–15.

(8) Bu, R. P.; Liu, G. R.; Zhang, C. Y. Relationship between the Molecular Structure and Stacking Mode: Characteristics of the D2h and D3h Molecules in Planar Layer-Stacked Crystals. Cryst. Growth Des. 2021, 21(12), 6847–6861.

(9) Bu, R. P.; Xie, W. Y.; Zhang, C. Y. Heat-Induced Polymorphic Transformation Facilitating the Low Impact-Sensitivity of 2,2-Dinitroethylene-1,1-diamine (FOX-7). J. Phys. Chem. C 2019, 123(26), 16014–16022.

(10) Bu, R. P.; Zhou, X. Q.; Li, H. Z. Measurement, Correlation and Thermodynamics of Solubility of 2,6-Diamino-3,5-Dinitropyrazine-1-Oxide (LLM-105) in Eight Solvents. Propellants Explos. Pyrotech. 2017, 42(12), 1347–1351.

(11) Bu, R. P.; Zhou, X. Q.; Li, H. Z. Measurement, Correlation and Thermodynamics of Solubility of 2,6-Diamino-3,5-Dinitropyrazine-1-Oxide (LLM-105) in Eight Solvents (vol 42, pg 1347, 2017). Propellants Explos. Pyrotech. 2018, 43(9), 962–962.

(12) Wang, C.; Bu, R. P.; Huang, F. Lipid-Mimicking Fluorescent Probe for Selective Bacterial Imaging and Rapid Antibiotic Screening. Anal. Chem. 2026, 98(3), 2318–2327.

(13) Li, S. J.; Bu, R. P.; Zhang, C. Y. Hirshfeld Surface Method and Its Application in Energetic Crystals. Cryst. Growth Des. 2021, 21(12), 6619–6634.

(14) Yang, B.; Xi, S. S.; Yang, G. C. Formation of flake-like DAAF crystals with tunable size realized on a microfluidic platform for binder-free initiator explosives. Chem. Eng. J. 2024, 499.

(15) Xu, J.; Su, J. S.; Zhao, Y. N. Phase Separation Investigation of Axitinib in Supersaturated Solution. Crystals 2024, 14(12).

(16) Wu, H. Q.; Wang, Z. P.; Han, J. Effect of different seed crystals on the supersaturation state of ritonavir tablets prepared by hot-melt extrusion. Eur. J. Pharm. Sci. 2023, 185.

(17) Qu, B. B.; Wu, H. Q.; Wang, Z. P. Amorphous solid dispersion formulation of pimobendan for bioavailability enhancement: A comprehensive study on miscibility, interactions, and in vitro dissolution behavior. J. Drug Deliv. Sci. Technol. 2025, 108.

(18) Zhong, K.; Bu, R. P.; Zhang, C. Y. Toward the defect engineering of energetic materials: A review of the effect of crystal defects on the sensitivity. Chem. Eng. J. 2022, 429.

1. 布汝朋, 周小清, 李洪珍, 郝世龙, 徐容, 陈东, 中粗颗粒高品质2,6-二胺基-3,5-二硝基吡嗪-1-氧化物炸药的制备方法, 2018.10.14, 中国，ZL201610898109.0. 

1. 张朝阳，黄静，布汝朋. 含能材料的本征结构与性能. 北京: 科学出版社，2022.

2. Chaoyang Zhang, Jing Huang, Ruepng Bu. Intrinsic Structures and Properties of Energetic Materials. Singapore: Springer Singapore, 2022.

1. 2020年获得“中物院科技创新二等奖”（部级）

2. 2022年获得“北京市优秀毕业生”（省级）