博士 / 讲师

    邮箱：meileixia09@163.com

教育及工作经历：

2020.10-至今       聊城大学，生物制药研究院，讲师

2014.09-2019.07  中国药科大学，药物分析，博士

2009.09-2013.07  山东农业大学，制药工程，学士

研究方向：

（1）多肽可控自组装的设计；

（2）智能凝胶递药系统研究；

承担项目：

聊城大学博士及高层次人才科研启动基金，2020/12-2023/12，主持

发表文章：

[1] Leixia Mei, Suyun He, Ziqi Liu, Keming Xu* and Wenying Zhong*. Co-assembled supramolecular hydrogels of doxorubicin and indomethacin-derived peptide conjugates for synergistic inhibition of cancer cell growth. Chemical Communications. 2019;55:4411-4414.

[2] Leixia Mei, Suyun He, Li Zhang, Keming Xu* and Wenying Zhong*. Doxorubicin-reinforced supramolecular hydrogels of RGD-derived peptide conjugates for pH-responsive drug delivery. Organic & Biomolecular Chemistry. 2019;17:3853-3860.

[3] Leixia Mei, Keming Xu (co-first author), Ziran Zhai, Suyun He,Tingting Zhu and Wenying Zhong*. Supramolecular self-assembly of fluorescent peptide amphiphiles for accurate and reversible pH measurement. Organic & Biomolecular Chemistry. 2019;17:939-944.

[4] Suyun He, Leixia Mei, Can Wu, Mingtao Tao,Ziran Zhai,Keming Xu*and Wenying Zhong*. In situ hydrogelation of bicalutamide-peptide conjugates at prostate tissue for smart drug release based on pH and enzymatic activity. Nanoscale. 2019;11:5030-5037.

[5] Ziran Zhai,‡ Keming Xu, ‡ Leixia Mei, Can Wu, Jing Liu, Ziqi Liu, Lanxin Wan  and Wenying Zhong*. Co-assembled supramolecular hydrogels of cell adhesive peptide and alginate for rapid hemostasis and efficacious wound healing. Soft Mater. 2019,15: 8603-8610.

[6] Mingtao Tao, Suyun He, Jing Liu, Hongmei Li, leixia Mei, Can Wu, Keming Xu, Wenying Zhong*. The conjugates of forky peptides and nonsteroidal anti-inflammatory drugs (NSAID) self-assemble into supramolecular hydrogels for prostate cancer-specific drug delivery. Journal of Materials Chemistry B. 2019,7:469-476.

[7] Junling Wang, Ran Wang, Fangrong Zhang, Yajun Yin, Leixia Mei, Fengjuan Song, Mingtao Tao,  Wanqing Yue and  Wenying Zhong*.Overcoming multidrug resistance by a combination of chemotherapy and photothermal therapy mediated by carbon nanohorns. Journal of Materials Chemistry B. 2016;4:6043-6051.