丁壮
作者: 发布时间:2022-03-29
博士/副教授/ 研究生导师 |
聊城大学“光岳英才计划” |
聊城市高新区“3111”工程高端人才 |
邮箱:dingzhuang@lcu.edu.cn |
教育及工作经历:
2016~至今,聊城大学,生物制药研究院
2010~2016,中国海洋大学,医药学院,医学博士
2005~2009,山东师范大学,生命科学学院,理学学士
主要研究方向:
(1)新型天然生物活性物质的发现研究
(2)天然活性物质的功能性创新制剂研发
教学科研项目情况:
(1)山东省自然科学基金面上项目,ZR2021MD123,2022/01-2024/12,主持
(2)山东省自然科学基金博士基金,ZR2017BB077,2018/01-2019/12,主持
(3)国家重点实验室开放课题,SKL-BASS1705,2017/07-2019/06,主持
(4)山东省抗体制药协同创新中心开放课题,CIC-AD1841,2018/1-2020/12,主持
(5)聊城大学博士科研启动经费,318051634,2017/01-2019/12,主持
(6)聊城大学研究生教育教学改革研究项目,2021/10-2023/10,主持
代表性论文:
(1) Xiao Wang, Zhuang Ding*, Yanna Zhao a , et al. Effects of lutein particle size in embedding emulsions on encapsulation efficiency, storage stability, and dissolution rate of microencapsules through spray drying. LWT - Food Science and Technology, 2021, 146, 111430. (SCI 一区)
(2) Zhuang Ding*, Tao Tao, Xiaohan Yin, et al. Improved encapsulation efficiency and storage stability of spray dried microencapsulated lutein with carbohydrates combinations as encapsulating material. LWT - Food Science and Technology, 2020, 124, 109139. (SCI 一区)
(3) Zhuang Ding*, Tao Tao, Xiao Wang, et al. Influences of different carbohydrates as wall material on powder characteristics, encapsulation efficiency, stability and degradation kinetics of microencapsulated lutein by spray drying. International Journal of Food Science and Technology, 2020, 55, 2872–2882. (SCI 二区)
(4) Zhuang Ding*, Xiao Wang, Fan-Dong Kong, et al. Overexpression of global regulator Talae1 leads to the discovery of new antifungal polyketides from endophytic fungus Trichoderma afroharzianum. Frontiers in Microbiology, 2020, 11, 622785. (SCI 二区)
(5) Zhuang Ding*, Haibo Zhou, Xiao Wang, et al. Deletion of the histone deacetylase HdaA in endophytic fungus Penicillium chrysogenum Fes1701 induces the complex response of multiple bioactive secondary metabolite production and relevant gene cluster expression. Molecules, 2020, 25, 3657. (SCI 三区)
(6) Tao Tao, Zhuang Ding*, Danping Hou, et al. Influence of polysaccharide as co-encapsulant on powder characteristics, survival and viability of microencapsulated Lactobacillus paracasei Lpc-37 by spray drying. Journal of Food Engineering, 2019, 252, 10–17. (SCI 一区)
(7) Zhuang Ding, Lili Wang, Yangyang Xing, et al. Enhanced Oral Bioavailability of Celecoxib Nanocrystalline Solid Dispersion based on Wet Media Milling Technique: Formulation, Optimization and In Vitro/In Vivo Evaluation. Pharmaceutics, 2019, 11, 328. (SCI 二区)
(8) Zhuang Ding*, Tao Tao, Lili Wang, et al. Bioprospecting of Novel and Bioactive Metabolites from Endophytic Fungi Isolated from Rubber Tree Ficus elastica Leaves. Journal of Microbiology and Biotechnology, 2019, 29(5), 731. (SCI 四区)
(9) Zhuang Ding, Liyuan Li, Qian Che, et al. Richness and bioactivity of culturable soil fungi from the Fildes Peninsula, Antarctica. Extremophiles, 2016, 20, 425–435. (SCI 三区)
(10) Zhuang Ding, Lianqing Zhang, Juan Fu, et al. Phenylpyropenes E and F: new meroterpenes from the marine-derived fungus Penicillium concentricum ZLQ-69. Journal of Antibiotics, 2015, 68, 748-751. (SCI 三区)