博士 / 讲师

邮箱：chaowang_0102@163.com

通讯地址：山东省聊城市湖南路1号

邮政编码：252059

教育及工作经历：

2022.07-至今     聊城大学，生物制药研究院，讲师

2018.07-2022.06  南开大学，化学学院，高分子化学与物理，博士学位

2015.09-2018.06  中国石油大学（华东），化工学院，生物工程，硕士学位

2011.09-2015.06  青岛农业大学，生命科学学院，生物技术，学士学位

研究方向：

新型功能性有机/高分子荧光材料的构建及其生物医药应用：

1. 环境响应型光敏剂的设计、合成及生物活性研究；

2. 极性敏感型荧光探针的设计、合成及生物传感研究；

3. 基于天然蛋白的药物靶向递送体系的构建及药物化学研究。

科研项目情况：

1. 聊城大学博士及高层次人才科研启动基金，318052260，2013.12.31-2025.12.31，主持。

2. 山东省自然科学基金青年项目，R2023QB269，2024.01.01-2026.12.31，主持。

发表论文：

16. Chengkun Liu, Jie Li, Zhuang Shi, Chao Wang, Jiqiang Li, Xiaoqiang Wang*, Fang Huang. Sprayable Macroporous Alginate/Chitosan Stacked Hydrogels for Enhancing Wound Healing. International Journal of Biological Macromolecules 2025, 319, 145678.

15. Na Fan, Da Song, Huairong Ding, Hongli Yang, Cong Xu, Chao Wang, and Yikun Yang*. E-jet 3D printed aligned nerve guidance conduits incorporated with decellularized extracellular matrix hydrogel encapsulating extracellular vesicles for peripheral nerve repair. Acta Biomaterialia 2025, 194,122–139.

14. Ke Xue, Siwei Huang, Kaiyu Wu, Zhencheng Sun, Hao Fu, Cheng Wang, Chao Wang, and Chunlei Zhu*. Ultrasensitive Ratiometric Fluorescent Nanothermometer with Reverse Signal Changes for Intracellular Temperature Mapping. Anal. Chem. 2024, 96, 11026–11035.

13. Jiaxin Wang, Liang Tian, Kaiyu Wu, Chao Wang, and Chunlei Zhu*. Reconstituting Low-Density Lipoprotein with NIR-Absorbing Organic Photothermal Agents for Targeted Killing of Cancer Cells. Macromol. Rapid Commun. 2023, 2300395. (SCI二区) DOI: 10.1002/marc.202300395.

12. Shuyi Lv, Chao Wang, Ke Xue, Jiaxin Wang, Ming-hui Xiao, Zhencheng Sun, Lei Han, Linqi Shi, and Chunlei Zhu*. Activated alkyne-enabled turn-on click bioconjugation with cascade signal amplification for ultrafast and high-throughput antibiotic screening. Proc. Natl. Acad. Sci. U.S.A., 2023, 120, e2302367120. (SCI一区，Top) DOI: 10.1073/pnas.2302367120.

11. Binghong He, Chao Wang, Fuping Wang, Liang Tian, Haitao Wang, Chunling Fu, Jin Liu, Chao Xi, Chunlei Zhu,* and Qiong Yang*. Differentiation Therapy for Murine Myelofibrosis Model with MLN8237 Loaded Low-density Lipoproteins. J. Control. Release, 2023, 356, 554–566. (SCI一区，Top) DOI: 10.1016/j.jconrel.2023.03.024.

10. Chao Wang, Xianhao Zhao, Kaiyu Wu, Shuyi Lv, and Chunlei Zhu*. A Ratiometric Organic Fluorescent Nanogel Thermometer for Highly Sensitive Temperature Sensing. Biosensors, 2022, 12, 702. (SCI二区) DOI: 10.3390/bios12090702.

9.  Chao Wang, Jiaxin Wang, Ke Xue, Ming-hui Xiao, Kaiyu Wu, Shuyi Lv, Boyi Hao, and Chunlei Zhu*. Polarity-Sensitive Fluorescent Probe for Reflecting the Packing Degree of Bacterial Membrane Lipids. Anal. Chem., 2022, 94, 3303–3312. (SCI一区，Top) DOI: 10.1021/acs.analchem.1c05268.

8. Boyi Hao, Jiaxin Wang, Chao Wang, Ke Xue, Ming-hui Xiao, Shuyi Lv, and Chunlei Zhu*. Bridging D‒A type photosensitizers with the azo group to boost intersystem crossing for efficient photodynamic therapy. Chem. Sci., 2022, 13, 4139–4149. (SCI一区，Top) DOI: 10.1039/D2SC00381C.

7.Ke Xue, Chao Wang, Jiaxin Wang, Shuyi Lv, Boyi Hao, Chunlei Zhu,* and Ben Zhong Tang*. A Sensitive and Reliable Organic Fluorescent Nanothermometer for Noninvasive Temperature Sensing. J. Am. Chem. Soc., 2021, 143, 14147–14157. (SCI一区，Top) DOI: 10.1021/jacs.1c04597. 

6. Chao Wang, Xianhao Zhao, Haoyu Jiang, Jiaxin Wang, Weixiu Zhong, Ke Xue, and Chunlei Zhu*. Transporting mitochondrion-targeting photosensitizers into cancer cells by low-density lipoproteins for fluorescence-feedback photodynamic therapy. Nanoscale, 2021, 13, 1195–1205. (SCI一区，Top) DOI: 10.1039/D0NR07342C.

5. Xiaoqiang Wang, Shixin Li, Chao Wang, Christopher J. Mujuni, Tongtao Yue*, and Fang Huang*. Supramolecular Construction of Biohybrid Nanozymes Based on the Molecular Chaperone GroEL as a Promiscuous Scaffold. ACS Biomater. Sci. Eng., 2020, 6, 833–841. (SCI二区) DOI: 10.1021/acsbiomaterials.9b00997.

4. Xiaoqiang Wang*, Haiyan Sun, Chengkun Liu and Chao Wang. A hemin-functionalized GroEL nanocage as an artificial peroxidase and its application in chromogenic detection. Anal. Methods, 2019, 11, 2197–2203. (SCI三区) DOI: 10.1039/C9AY00201D.

3.Xiaoqiang Wang, Chao Wang, Baomei Xu, Junting Wei, Yang Xiao, Fang Huang*. Adsorption of intrinsically disordered barnacle adhesive proteins on silica surface. Appl. Surf. Sci., 2018, 427, 942–949. (SCI一区，Top) DOI: 10.1016/j.apsusc.2017.08.108.

2.Xiaoqiang Wang, Chao Wang, Meihong Pan, Junting Wei, Fuping Jiang, Rongsheng Lu, Xuan Liu, Yihui Huang, and Fang Huang*. Chaperonin-Nanocaged Hemin as an Artificial Metalloenzyme for Oxidation Catalysis. ACS Appl. Mater. Interfaces, 2017, 9, 30, 25387–25396. (SCI一区，Top) DOI: 10.1021/acsami.7b08963.

1.Xiaoqiang Wang, Yang Xiao, Chao Wang, Jianjie Niu, Jing Ma, Haodong Wang, Xinwei Li, Xue Chen, Fang Huang*. Hierarchical interfacial structuring of the calcareous base of the barnacle Balanus albicostatus over different length scales. Mater. Chem. Phys., 2017, 192, 48–57. (SCI三区)  DOI: 10.1016/j.matchemphys.2017.01.053.